Pharmacy education and business address the challenges in making a safer, sustainable and affordable system for drug manufacturing, medication, and healthcare through strengthening the foundation of pharmacy research platforms. Researcher and Expertise these need in-depth understanding of their skills and embarking their lifelong learning to achieve novel therapeutic plans. The Global Pharma Summit provides a platform to all members of thehealthcare system to share and exchange their knowledge and ideas. It also reinforces the importance of collaboration and dialogue between Policy Makers, Stakeholders, and Regulators from related fields to ensure planning, implementation, and monitoring of a therapeutic plan that focuses on effective patient outcome.
This scientific session will give an opportunity to the coming scientists to share their new ideas and information about many established and emerging pharmaceutical fields such as pharmaceutical product development, IPDO, dendrimers, novel drug delivery system, drug targeting, pharmacovigilence and bioequivalence, molecular modelling, computer aided drug designing and molecular modelling. It will also emphasise over academia industrialization.
In addition to attending the conference, we invite you to experience Bangkok, the beautiful and famous city in Thailand, which attracts people from around the world.
- Students, Scientists, Research scholars and Faculties from pharmacy Universities, Medical Colleges.
- Research scientists from pharmaceutical Industries.
- Pharmacy associations and societies.
- Business Entrepreneurs.
- Training institutes.
- Software developing companies.
- Medical devices manufacturing companies.
- Clinical Research Organizations.
- Data Management companies.
- Association of pharmacy Technicians
- Austrian pharmaceutical Society
- American Association of Colleges of pharmacy
- International Council of Chemical Associations
- Association of Greek Chemists
- European Association of Chemical and Molecular Sciences
- Pharmaceutical Society of Ireland
- The International Society for Pharmaceutical Engineering (ISPE)
- The European Generic Medicines Association (EGA)
- The European Personalised Medicine Association EPEMED
- European Association of Employed Community Pharmacists in Europe (EPhEU)
- European Pharmaceutical Union (EPU)
- Pharmaceutical Group of the European Union (PGEU)
- European Confederation of Pharmaceutical Entrepreneurs (EUCOPE)
- Drug Information Association (DIA)
- European Generic Medicines Association
- European Federation of Pharmaceutical Industries and Associations (EFPIA)
- European Pharmaceutical Market Research Association (EphMRA)
- International Federation of Pharmaceutical Manufacturers and Associations (IFPMA)
- Japan Pharmaceutical Manufacturers Association (JPMA)
- New York Health Products Council (NYHPC)
- Pharmaceutical Research and Manufacturers of America (PhRMA)
- Irish Pharmaceutical Healthcare Association (IPHA)
Allied Academies cordially welcomes all the attendees, speakers, sponsor’s and other research expertise from all over the world to the “Global Pharma Summit” (Pharma Summit 2018) which is going to be held during June 25-26, 2018 in Bangkok, Thailand. We are very much honored to invite you all to exchange and share your views and experience in Pharmaceutics: “Advanced Pharma Technologies-Better Healthcare system”.
Allied Academies Organizes Pharma Summit- 2018 conference along with 300+ Conferences across the USA, Europe & Asia every year with support from 1000 more scientific societies and Publishes 400+ Open access journals which contain over 30000 eminent personalities as editorial board members.
We invite you to join us at the Pharma Summit-2018, where you will be sure to have a meaningful experience with scholars from around the world. All members of the Pharma Summit-2018 organizing committee look forward to meeting you in Bangkok, Thailand.
Sessions & Tracks
Session 1. Pharmaceutical Industry Academia Collaboration:
We want pure science with capital. Research done by students, professors in colleges, universities and hospitals is an academic research on the other hand pharmaceutical industries deals with the discovery, development, production and finally sale of drug. For the development of new active pharmaceutical ingredient, the collaboration of academic research work andpharmaceutical industries is needed. The new drug discovery and development is very long process and is also based on our basic understanding of biological mechanism and identification of therapeutic targets. The flux of pharmaceutical industries has changed a lot over last 30 years. There has been hike in investments and fall in coming revenue for research and development section. The production of Merck, Eli Lilly, and Roche has remained constant over the last 60 years with one drug per year by each company. A marketed product cannot assure market benefit for further hundreds of years. Hence innovation is extremely important for such industries and this innovation comes from an academic research. Academic invention should be broadcasted to the industries so that its applications may get applied in healthcare systems.
Biotherapeutic drug delivery system uses drug molecules made prepared from living organism naturally or in the laboratory. Fusion proteins, antibodies and therapeutic replacement enzymes are the major used bio therapeutic agents. Human insulin is the first bio therapeutic drug developed by recombinant-DNA technology and was approved by Eli Lily. These drugs have bought boom in the treatment of cancer, autoimmune disease, inflammatory diseases, haemophilia, cardio vascular disease and some genetic disorders. These drugs are differentiated as non-immune proteins, peptides and small therapeutic proteins and therapeutic antibodies and Fc- like fusion proteins. These bio therapeutic drugs act by different mechanism of actions like direct enzyme replacement, effector functions, cytokine and growth factor blockage, receptor blockage and modulation, toxin conjugation, stimulation of biological signal responses or by an enzyme inhibition. Hybridomas, human antibodies from mice, chimerization, humanization, glycoengineering and intrbodies are some carriers used in this drug delivery system.
- Biotherapeutics generation Tools
- Safety and side effects of biotherapeutics
- Focused Ultra sound (FUS) technology
- Transcranial Brain Drug Delivery
- Intranasal Delivery
- Endocytosis and Transcytosis (Adsorptive and Receptor Mediated)
- Chemical Delivery Systems
Session 3: Green and Sustainable Pharmacy Practice:
Pharmaceutical drugs are now days considered to cause environmental problems if not used properly or disposed in appropriate manner. Sustainable chemistry is also under consideration. These two altogether comprises sustainable pharmacy. The green pharmacy practice was initiated by FIP (International Pharmaceutical Federation) which includes pharmacists and pharmaceutical scientists from all around the world. FIP develops practical methods to deal with pharmaceuticals and the environment. It provides important information and tools to the pharmacists for taking environmental issues into an eye in their daily professional activities. Sustainable pharmacy describes environmental, economic and social aspects of pharmacy. It deals all the environmental issues along the whole lifecycle of a pharmaceutical drug moiety.
Session 4: Integrated Product Development:
Our pharmaceutical industries are facing challenges like acceleration of time-to-market and integrated global development for achieving novel healthcare products. Now a day’s healthcare system is the main global issue. They are reducing the costs and also made the regulations and guidelines strict for pricing of any healthcare product and taking reimbursement. These amendments in rules are showing their effect on market access and the cost of medicinal products. Calculated planning is one is necessary for any kind of drug development, conventional medicinal products or biopharmaceuticals. An integrated development plan is a key step which covers pharmaceutical manufacturing and its control, non-clinical and clinical aspects, the Target Product Profile (TPP) and marketing and commercial factors. Integrated Product Development Plan defines the goals and important claims of medicinal product
Session 5. Pharmaceutical Quality by Design (QbD):
Quality indicates fit to use. The quality of any pharmaceutical product means that it should be contamination free and its therapeutic benefits are reproducible as per the claim on its label. Its quality is evaluated In vitro and In vivo. The in vitro performance of a product is evaluated by Quality by design and this In vitro product performance gives information of In vivo product performance, so Quality by design assures about the whole product performance. It is a systematic approach to development starting with pre-planned agendas and centers over the understanding product, process and process control, on the basis of established scientific technology and quality risk management. It has come to practice to promote safe and effective drug supply and also claims to significantly improve manufacturing quality performance.
Session 6: Nano Drug Delivery System:
Nanoparticles carry encapsulated, dispersed or conjugated drugs having important properties which can enhance performance in a variety of dosage forms. They can be used for both passive and active drug targeting. Cell-specific targeting can be accomplished by attaching drugs to specially designed carriers and site-specific drug targeting can be achieved by attaching target ligands, such as aptamers or antibodies to the surface of nanoparticles. Nanostructures such as liposomes, polymers, Dendrimers, silicon or carbon materials, and magnetic nanoparticles are used as carriers in nano drug delivery systems and provide cell-specific targeting. Nanoparticles are smaller than 100 nm. They have size range similar to proteins and other macromolecular structures within the living cells. The nanostructures have the property to enhance their reaction area and they can also cross cell and tissue membrane. Due to these physicochemical and biological properties nanostructures are used for biomedical applications. One of the widely applied nanotechnologies is nanomedicine, which implement nano drug delivery technique to highly specific medical practices.
- Nanoelectromechanical system
- Molecular nanotechnology
- Nanotechnology in Cancer Treatment
- Heart nanotechnology
- Nanotechnology in Tissue Engineering
- Artificial DNA Nanostructures
Session 7: Medicine Development and Safety Testing:
Advancement of drug is a crucial worry to prescription, yet in addition has solid sparing and political ramifications. To ensure the purchaser and anticipate manhandle, numerous legislatures direct the produce, deal, and organization of drug. In the United States, the primary body that directs pharmaceuticals is the Food and Drug Administration and they implement measures set by the United States Pharmacopeia. In the European Union, the primary body that manages pharmaceuticals is the EMA and they uphold guidelines set by the European Pharmacopeia.
- Metabolic Stability
- Drug metabolism
- Structural activity relationship (SAR)
Session 8: Medical Devices for Drug Delivery:
A medical device is any instrument, device, apparatus, programming, material or other article, regardless of whether utilized alone or in blend, including the product planned by its maker to be utilized particularly for indicative as well as remedial purposes and fundamental for its legitimate application, expected by the producer to be utilized for individuals for the reason of: Diagnosis, counteractive action, observing, treatment or lightening of disease; Diagnosis, checking, treatment, easing of or remuneration for damage or handicap; investigation, substitution or change of the life structures or of a physiological procedure; Restorative gadgets shift as per their planned utilize and signs. Illustrations extend from basic gadgets, for example, tongue depressors, therapeutic thermometers, and dispensable gloves to cutting edge gadgets, for example, PCs which aid the lead of restorative testing, inserts, and prostheses. The outline of restorative gadgets constitutes a noteworthy section of the field of mechanical building.
- Biomedical Instrumentation Measurements
- Measurement of Blood Flow and Cardiac Output
- Instrumentation for Psychophysiological Measurements
- Instrumentation for the Experimental Analysis of Behaviour
- Respiratory Therapy Equipment
- Pacemakers and Defibrillators
- Instrumentation for the Medical Use of Radioisotopes
- Ophthalmic and ENT Instruments
- Computed Tomographic Scanning (CT Scanning)
- Positron-Emission Tomographic (PET) Scanning
Session 9: Robotic Process Automation:
The pharmaceutical industries all over the world are trying to implement the automation of processes by robotics. Robotic process automation is software comprising of commands which communicates with the digital system that further help to complete the process-oriented task more efficiently compared to human. It helps to perform many tasks automatically which were to be performed repetitively. Business process outsourcing industry will be benefited with this technology. The invention of Robotic process automation has change the scenario of pharmaceutical business by starting with implement of„robots” to accomplish huge amount of work and also repeatable tasks which are done by man power earlier. It will provide fast and secure method to perform recurring processes in an efficient manner. This will help pharmaceutical industries to provide safe healthcare products at low cost.
Eastern Europe is a popular location to perform clinical trials and medical research. The clinical research organization work includes research monitoring, data collection the pharmaceutical industry, as study management and project planning resource tool with additional responsibilities. In Eastern Europe the main work of clinical research organizations is the recruitment and training of clinical investigators, clinical research professionals, and to ensure that studies are managed and conducted to the highest possible industry standards. There will be expected high demand of medical professionals and trained workers in the clinical trial industry and hence Eastern Europe will be promoted as a major center for the of clinical research work.
- Proof-of-concept testing
- Bioavailability and Bioequivalence studies
- Medical writing
- Medical Coding
- Risk management services
- Serious Adverse Drug Event Processing
- Drug Safety data base management
- Clinical Study Reports
- Periodic Safety Reports
- Clinical Data Management
- Good Laboratory practice and Good Clinical Practice
Session 11: Biomedicine and Pharmacotherapy:
Biomedicine and pharmacotherapy is the science which manages and deals with the principal and specialized science, organic and medicinal orders, therapeutics and neurotic depiction. General Fields of intrigue incorporate atomic and cell science, hereditary malady, immunology and immunoregulation, growth, chemotherapy, nutraceuticals, neurodegenerative, heart and Infectious Diseases. Exceptional accentuation is put on investigations of particular subjects, for example, separation, pharmacology and toxicology, preclinical and clinical pharmacology, the impacts of medications on cell basic and practical components, the instrument of quality direction in typical and neurotic cells, the part of infections and parasites and the treatment of the maladies they initiate.
- Neurodegenerative Disease
Session 12: Vaccine Drug Delivery System:
Vaccine is a material that induces an immunologically mediated resistance to a disease but not necessarily an infection.Vaccines are generally composed of killed or attenuated organisms or subunits of organisms or DNA encoding antigenic proteins of pathogens. Sub-unit vaccines though exceptionally selective and specific in reacting with antibodies often fail to show such reactions in circumstances such as shifts in epitopic identification centre of antibody and are poorly immunogenic. Delivery of antigens from oil-based adjuvants such as Freunds adjuvant lead to a reduction in the number of doses of vaccine to be administered but due to toxicity concerns like inductions of granulomas at the injection site, such adjuvants are not widely used. FDA approved adjuvants for human uses are aluminium hydroxide and aluminium phosphate in the form of alum. Hence, search for safer and potent adjuvants resulted in the formulation of antigen into delivery systems that administer antigen in particulate form rather than solution form.
- Polymers in solid particulate vaccine delivery
- Emulsion Delivery System
- Micellar Delivery System
- Immunostimulatory Complexes
- Edible vaccines
- DNA Vaccine Delivery System
- Mucosal Vaccine Delivery
- Needle-free vaccine delivery
- Jet Injectors
- Melt in Mouth Strips
Session 13: Drug Designing:
Drug design also called as rational drug design is the process of discovering new drug on the basis of knowledge of biological target organs. It deals with the design of molecules, complementary to the bimolecular target in shape and charge so that they could interact and get easily bind to each other. Drug designing is based on computer modelling techniqueswhich are also termed as computer-aided drug design. Drug design which is based on the three-dimensional structure of the bimolecular target is called as structure-based drug design. Drug targeting works with therapeutic approach and also as a research tool to use the properties of these techniques in physiology and patho-physiological conditions.
- Computer-aided drug design
- Structure-based drug design/Direct drug design
- Ligand based drug design/Indirect drug design
Session 14: Pharmacokinetics and Drug Interaction:
Drug interaction occurs when the effect of one drug is altered by the other drug or any food supplement taken that time.Drug interaction may be drug-food or drug-drug interaction. It can also synergistic or antagonistic drug interaction. In pharmacokinetic drug interaction the absorption, distribution, metabolism or excretion of a drug is altered by other drug, or any food item. This type of drug interaction may further affect the therapeutic effects or toxic effect of the particular drug. In pharmacodynamics, pharmacological effects of a drug may alter, as this type of drug interaction is related to target body organ.
- Clinical pharmacokinetics
- Effect of Renal and Hepatic Disease on Pharmacokinetics and Pharmacodynamics
Session 15: Clinical Pharmacology and Therapeutic Systems:All the medical practitioners prescribe medicaments and drugs to treat patient’s disease. Hence to ensure safe and effective therapeutic practice, it is indispensable for all the members of medical and pharmaceutical curriculum to understand the principles and drug science which is also called clinical pharmacology. Clinical pharmacology includes drug metabolism, drug interaction, drug disposition, adverse drug reactions, gene and cell based drug therapies and many more contents.
- Plasma protein binding
- Dose–response relationship
- Drug development and regulation
- Clinical trials
- Yellow card scheme
- Translational research
- Management of Coronary Artery Disease and its Complications
- Drugs and gastrointestinal disease
- Psychiatric Disorders and Treatment
- Antimicrobial therapy
- Travel medicine and tropical disease
- Cancer therapeutics
- Inflammatory joint disease
Session 16: Novel Targeted Drug Delivery Systems:
The field of therapeutics has been radically transformed by the advent of novel techniques for drug delivery. Targeted or site specific drug delivery refers to place the drug to the desired body tissue. In this delivery system dose of medicament is reduced as its required concentration is increased at the target site only, hence it also minimizes the side effects of the drug and improved its therapeutic efficacy. Quantum dot, Transdermal devices are some of the aspects of targeted drug delivery. Pulmonary drug delivery routes are increasing importance.
- Carriers or Markers for Targeted Drug Delivery
- Types of Targeted Drug Delivery Systems
- Biodegradable particles
- Magnetic drug delivery
- Retrometabolic drug design
- Transdermal Drug Delivery
Session 17: Pre-formulation and Product Development:
The pre-formulation is the very first and most important step of any formulation development. It decides the stability, integrity and quality of any dosage from and also the success of any of the product development process. Pre-formulationstudies from the route stop like solubility testing, bulk density, polymorphism, angle of repose to the endorsement of biopharmaceutical information so as to decide appropriate formulation compositions, excipients, polymers, dosage form, process methods, evaluation techniques and finally packaging standards and marketing. It reduces the chance of mistakes and material wastage while formulation. The process of pre-formulation and optimization has become easier by the exploration of novel software techniques. The whole range of steps involved from pre-formulation studies to manufacturing and evaluation of dosage form is called formulation development.
- Drug-Excipient Compatibility Studies
- Stability Studies
- Solubility Enhancement
- Crystalinity and Polymorphism
- Dissolution Studies
- Analytical Methods
- Tablet Technology
Session 18: Pharmaceutical and Hospital Pharmacy Management:
Professionals under pharmaceutical management portfoliate monitory as well as business decisions for the research and development of new drug, its marketing, and sales. They plan the strategies for the commercialization of new drug after its approval from Food and Drug administration (FDA). Carrier in this field also includes:
- Natural sciences manager
Hospital pharmacy management deals with the management of using medicines and different healthcare related techniques. The drug and therapeutics committee (DTC) develops various policies and procedures for the promotion rational medicine.
Session 19: Clinical and Hospital Pharmacy:
Application of drug medication methods to the patients in hospitals and clinical organization is referred as clinical andhospital pharmacy. This practice also involves the aid of doctors and registered medical practitioners for the providing drug therapies to the patients. Pharmaceutical study is nothing but proper formulation, dispensing and administration of drug in an appropriate dosage form as it is responsible for the safety and health of patient. There is a vast career in this field such as pharmacist, clinical pharmacist, and paediatric clinical pharmacist.
Session 20: Natural Products and Biogenesis:
A chemical substances produced naturally by any living organism is termed as natural product. They have characteristic small molecular structures with specific biological activity. Taxol is a natural product. The synthesis and isolation of natural products and biologically active compounds is called as biogenesis and is an important fragment of modern chemistry. Different processes involved in biogenesis of natural products are:
- Characterization of natural products and bioactive compounds
- MS-based methods
- Activity profiling
- Chromatographic methods
- NMR based methods
- Biogenesis and classification of natural products
Session 21: Drug Regulatory Affairs:
Drug regulatory bodies in any pharmaceutical companies check every drug rigorously to ensure its safety, efficacy and quality. It thoroughly keeps an eye on every developing drug before its marketing and approval for clinical trials. Food and Drug Administration (FDA), Drug Controlling Authority (DCA), Medicine Control Agency (MCA), etc. are different regulatory bodies in US, India and UK respectively who set the standards for the quality and efficacy of every drug and its approval.
- Biocompatibility Assessment
- Process Validations
- QMS (Quality Management System) Development and Implementation
Session 22: Pharmaceutical Biotechnology:
Biotechnology is a science in which living organisms, biological systems or their derivatives are used to make or modify new products or process for any specific purpose. The application of biotechnology in the field of food, agriculture, and pharmaceuticals is wide spread. Biotech pharmaceutical products are prepared at molecular level by modifying living organisms. Protein based therapeutic system is supposed to be the future of pharmaceutical industries. Therapeutic proteins consists post translational modifications such as glycosylation of erythropoietin.
- Recombinant DNA Technology
- Gene Therapy
- Genetic Testing
- Protein Drug Delivery System
Global Pharmaceutical Market:
It is predicted that total expenditure on medicines will reach $1.5 trillion by 2021 and up to 33% from 2016 levels, but recently it is less than the high growth rates in 2014 and 2015. Medicament spending will grow at a 4% to 7% compound annual growth rate during the next five years, down from the nearly 9% growth level seen in 2014 and 2015. The short-term rise in growth in 2014 and 2015 was inspired by the development of new medicines in hepatitis and cancer that contributed strongly to growth but will show reduced impact through 2021. The total volume of medicines consumed globally will increase by about 3% annually through 2021. The total global spend for pharmaceuticals through 2021 will increase by $367 billion on a constant-dollar basis. Spending is measured at the ex-manufacturer level before adjusting for rebates, discounts, taxes and other adjustments that affect net sales received by manufacturers. The impact of these factors is estimated to reduce growth by $127 billion, or approximately 35% of the growth forecast through 2021.
U.S. Pharmaceutical Industry:
The pharmaceutical market of USA represents the largest continental pharma market worldwide, together with Canada and Mexico. It holds over 45 percent of the global pharmaceutical market. The market share for U.S. was valued around 446 billion U.S. dollars in 2016. The on the global market are Johnson & Johnson, Pfizer and Merck &Co. Johnson & Johnson are the largest pharmaceutical companies in the world pharma market. These Johnson & Johnson had generated around 72 billion U.S. dollars of revenue in 2016. It is also actively involved in the medical devices/diagnostics and consumer products segments. Approximately 60 billion U.S. dollars per year are utilized for the pharmaceutical R&D purposes in the U.S. The R&D expenditures per employee in the pharma industry are higher than in any other manufacturing sector in the United States. In recent years, oncology, diabetes, and autoimmune are the three top therapy classes for which most money was spent. These three areas alone were worth over 110 billion U.S. dollars in 2015. Generics were the top drugs in 2015, on the basis of number of prescriptions, Such as Levothyroxine and Acetaminophen were prescribed a combined 218 million times in 2015.
European Pharmaceutical Industry:
In 2015 the Europe invested invested nearly € 33,600 million on research and development. A decade of strong US market dominance led to a shift of economic and research activity towards the US from 1995- 2005. Europe is now facing increasing competition from emerging economies: rapid growth in the market and research environments in countries such as Brazil and China are contributing to the move of economic and research activities to non-European markets. The geographical balance of the pharmaceutical market and ultimately the R&D base is likely to shift gradually towards emerging economies.
Asia Pacific Pharmaceutical Industry:
The Asia Pacific (APAC) pharmaceutical market has shown the modest growth in 2017. In 2017, medicine sales rose approximately by 5% year-on-year. The trends such as the roll out of universal healthcare and advances by private healthcare providers are expected to continue, shaping opportunities for the region. In addition, the pricing environment has become more dynamic as governments introduce more measures to control spending while meeting the demand for high-value pharmaceuticals.
Thailand Pharmaceutical Industry:
In 2016 Thailand spent over $2.2 billion in pharmaceuticals. It was a considerable increase from $1.8 billion just two years ago. Over 65% of Thailand’s pharmaceutical imports came from the United States, Europe, and Canada in 2016. The largest pharmaceutical exporter to Thailand was Germany and followed by the US, France, then Switzerland. The pharmaceutical market of Thailand was valued at over $5 billion in 2016, which made it as the second largest market in Southeast Asia. Thailand’s pharmaceutical market value is expected to double by 2020. Pharmaceutical sales per-capita are also expected to grow from $75 in 2016 to $125 by 2024.